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Category: Antimicrobial Resistance

Equipment used to make early forms of penicillin

Do You Really Need to Finish That Course of Antibiotics?

Posted on May 8, 2022May 8, 2022 by Jennifer Tsang

“Finish the entire course of antibiotics you were prescribed, even if you feel better.” You may have been told this by your doctor or have this saying deeply ingrained in your mind from infections past. You may also have been told that if you don’t finish your full course of antibiotics, your infection could come…

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The journey of a superbug gene to the Arctic

Posted on March 28, 2019July 3, 2022 by Jennifer Tsang

By Ananya Sen A straight walk from India to the Arctic is approximately 4,000 miles. The trip includes the hot and humid climate of India, the temperate and dry climate of central Europe, and finally the rugged and frozen tundra of Svalbard in the Arctic Circle. Imagine embarking on this adventure as a gene. Seem…

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Plasmid Addiction Systems Are Behind Bacteria’s Toxic Addiction to DNA

Posted on March 29, 2017August 6, 2022 by Jennifer Tsang

For bacteria, addiction to DNA can be a life or death situation. Lose that DNA and the bacterium suffers an unfortunate toxic death. Many bacteria easily transfer DNA amongst themselves in the forms of plasmid DNA. Plasmids are mobile genetic elements that replicate independently of the chromosome. These small circular pieces of DNA often contain…

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Eaten alive from the inside: predatory bacteria kill pathogenic bacteria from the inside out

Posted on December 12, 2016August 8, 2022 by Jennifer Tsang

When it comes to predators, we naturally think of large, agile, and powerful animals on the prowl. But we often don’t think about the most abundant predators on our planet, predators of the microscopic world. In the depths of the microbial universe, predatory bacteria (those that feast upon other bacteria) have emerged. These bacteria are…

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Solving the plasmid paradox: evolutionary advantages of multicopy plasmids

Posted on November 20, 2016August 8, 2022 by Jennifer Tsang

Today marks the end of 2016’s World Antibiotic Awareness Week, aimed to increase awareness of antibiotic resistance and to advocate for the prudent use of these drugs. One of the key drivers of antibiotic resistance is how rapidly bacteria acquire DNA from the environment or from other bacteria. Resistance elements are often carried on mobile…

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