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Are we more bacteria than human? That depends when you last pooped

Posted on October 11, 2018July 3, 2022 by Jennifer Tsang

For decades, the notion that bacteria living on our bodies outnumbered human cells 10 to 1 was popular among microbiologists and the public. Turns out, this estimation is wrong. In 2016, Ron Sender, Shai Fuchs, and Ron Milo from the Weizmann Institute examined the origins of this estimation and found that the ratio is actually…

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Meet Carsonella ruddii, a Microbe so Small That Might Not Even Be a Microbe

Posted on September 13, 2018May 19, 2026 by Jennifer Tsang

This post is part of the Meet a Microbe series on the blog. Check it out to meet other microbes! In 2006, Carsonella ruddii was reported as the smallest of the small: this microbe contains the smallest genome identified at the time, clocking in at 159,662 base pairs encoding 182 genes. The Escherichia coli genome on the…

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mRNA translation, ribosome, protein synthesis

Protein Translation Can Initiate From 17 Start Codons

Posted on August 1, 2018July 4, 2022 by Jennifer Tsang

In the realm of biology, we are always finding exceptions to the rule. And now, we have just added another exception to the central dogma of genetics. But first, let’s review what the central dogma is. The central dogma states that that the flow of genetic information goes from DNA to mRNA to protein. In…

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Seaweed and the Gut Microbiome: You are What You Eat

Posted on July 18, 2018May 14, 2026 by Jennifer Tsang

Our intestine is home to three pounds of bacteria (in fact, we have about equal numbers of bacteria and human cells in the body). We feed them and they feed us. They help us break down proteins, lipids, and carbohydrates from our food into nutrients that we can then absorb. Without them, we would not…

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Donating Your Poop for Science – Microbiome Studies

Posted on June 27, 2018July 4, 2022 by Jennifer Tsang

By Kanika Khanna In this journey called life, we are not alone. We are inhabited by around 39 trillion microbial cells that account for ~57% of all cells in our body, making us half human and half microbes. This consortium of microbial species (including bacteria, fungi, viruses, and archaea) is referred to as the ‘human…

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