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Why are pathogens rarely resistant to vaccines?

Posted on April 9, 2017August 6, 2022 by Jennifer Tsang

Updated May 22, 2021. We have all heard the horrifying tales of incurable bacterial infections due to antibiotic resistance. But why don’t we see pathogens becoming resistant to vaccines? Intuitively, it seems that vaccines, like antibiotics, put selective pressure on pathogens. The selective force should drive the evolution of vaccine resistance, right? David Kennedy and…

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Meet a microbiologist: Stéphane Benoit

Posted on April 5, 2017May 12, 2026 by Jennifer Tsang

Many graduate students call the lab their second home. I was fortunate enough to have a second “lab home”. Today, we meet Stéphane Benoit, a microbiologist from my second “lab home” who has taught me much of what I know about working with the stomach bacterium Helicobacter pylori. Growing up in the French village of…

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Plasmid Addiction Systems Are Behind Bacteria’s Toxic Addiction to DNA

Posted on March 29, 2017August 6, 2022 by Jennifer Tsang

For bacteria, addiction to DNA can be a life or death situation. Lose that DNA and the bacterium suffers an unfortunate toxic death. Many bacteria easily transfer DNA amongst themselves in the forms of plasmid DNA. Plasmids are mobile genetic elements that replicate independently of the chromosome. These small circular pieces of DNA often contain…

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Meet a microbiologist: Naomi Boxall

Posted on March 22, 2017May 12, 2026 by Jennifer Tsang

Naomi Boxall is not afraid to point out that the pictures of people in white lab coats with colorful vials of liquids do not show how real science is done. She’s had to take one of those pictures herself. Her time in science has led her to sample soil and water in the Western Australian…

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Deinococcus radiodurans Daly lab

Meet a microbe: Deinococcus radiodurans

Posted on March 16, 2017August 6, 2022 by Jennifer Tsang

Meet Deinococcus radiodurans, one of the world’s toughest bacterium. It’s an extremophile and one of the most radiation-resistant organisms known on Earth. This hardy little bacterium can survive over a thousand times the amount of radiation that would kill a human. Its tolerance to many harsh conditions has earned itself the name “Conan the Bacterium,”…

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